This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACGTCCTGTCCAGGATCATT and GCGTTGGTTGATATGCGCTA, which resulted in a 364 bp deletion beginning at Chromosome 5 position 23,775,824 bp and ending after 23,776,187 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000487336 (exon 3) and 279 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 132 and early truncation 9 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count