A targeting construct was designed to insert an internal ribosomal entry site (IRES) and a Cre Recombinase with a polyadenylation signal, followed by a frt-flanked neomycin resistance (neo) cassette, downstream of the stop codon of the corticotropin releasing hormone receptor 2 (Crhr2) gene. (J:101977, J:298576)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count