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The transgene construct used for the Tg(Myh6-cat)7Rbns and Tg(Myh6-cat)27Rbns alleles was modified to inactivate the Mef2a binding site located at -327..-314 (relative to the transcription start site). Using site-directed mutagenesis, wildtype binding site TTAAAAATAACTGA was changed to TGACCACTCCATGC. (J:4164)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
