An frt-flanked neomycin selection cassette was inserted upstream of exon 10 and loxP sites were inserted to flank exons 1-12. FLP-mediated recombination removed the neomycin selection cassette, leaving the loxP sites intact. (J:259650)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count