A loxP site and rox-flanked PGK-Hygromycin/Zeocin cassette were targeted to intron 1. A 2A peptide, tdTomato cDNA, SV40 polyA cassette, FRT-flanked PGK-Neo cassette, loxP, splice acceptor, EGFP cDNA, and rabbit beta-globin poly adenylation cassette were targeted to exon 12 immediately before the stop codon.Dre- and Flp-mediated recombination excised the rox- and FRT-flanked antibiotic resistance cassettes. (J:341391)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
Insertion
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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