A 5' loxP site was inserted in intron 1 at position 628 nucleotides 5' of exon 2, and the second 3' loxP site together with an frt-flanked PGK-neo selectable marker was inserted 140 nucleotides 5' of exon 7. Flp-mediated recombination removed the selection cassette, leaving exons 2-6 floxed. (J:272643)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129 x C57BL/6J)F1
Targeted
Insertion
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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