The targeting vector contains, from 5' to 3', an internal ribosome entry site sequence (IRES), the FLPo recombinase sequence (with nuclear localization signal at its 5' end), a bovine growth hormone polyA sequence and a lox2272-flanked PGK-Neo-bGHpA cassette inserted into the 3'UTR immediately following the STOP codon of the gene. Cre-mediated recombination removed the floxed neo cassette. (J:269094)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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