A targeting vector containing (from 5' to 3') a loxP-F3-puromycin Δtk-loxP-FRT was used to disrupt Mir574 on chromosome 5. Mir574 is located in intron 1 of the host gene Fam114a1. Cre-mediated recombination removed the floxed purumycin cassette. (J:174268)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
Insertion, Intragenic deletion
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--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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