The targeting vector is designed to insert a loxP site upstream of exon 4, and an FRT-flanked neomycin selection cassette followed by a second loxP site downstream of exon 5 of the gene. (J:283776)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count