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The targeting vector contains sequence encoding the mouse Gfi1 open reading frame, followed by an IRES-Venus (YFP variant) under the control of the tetO (tetracycline responsive element). The Gfi1-IRES-Venus vector is inserted into the 3' UTR of the Col1a1 locus using a FLP recombinase expression vector (pCAGs-FLPe-Puro), which also repairs a defective hygromycin resistance gene. (J:271545)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
