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This allele from project TCPR1260 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs with spacer sequences of TAAAAGAGCCATCTACGGGG and GTGTAAAACAGTCAATCGAG targeting the 5' side and CTTCGATCTGAAGAGTCGGG and GCACATCACTAGATAGCATG targeting the 3' side of a critical exon. This resulted in a 5-bp deletion on Chr8: 77413906 to 77413910, a 351-bp deletion on Chr8: 77413460 to 77413810, and a 3-bp deletion Chr8: 77413310 to 77413312 (GRCm38). (J:265051)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
