The transgenic construct contains (from 5' to 3') the Tet response element (TRE; ~600 bp sequence composed of direct repeats of the tet operator sequence [tetO] and minimal cytomegalovirus promoter sequence [Pmin]), a ~700 bp cDNA segment encoding the long isoform of the B cell leukemia/lymphoma 2 gene, an internal ribosome entry site, a tdTomato fluorescent protein and an SV40 polyA sequence. (J:271395)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count