A loxP site was inserted upstream of exon 3. An FRT-flanked puromycin reistance cassette with a 3' loxP site. Flp-mediated recombination removed the selection cassette and left exon 3 floxed. (J:238964)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count