A loxP site and frt-flanked neomycin selection cassette were inserted about 0.6-kb upstream of exon 5. A second loxP site was inserted about 240-bp downstream of exon 8. Flp-mediated recombination removed the neomycin cassette, leaving exons 5-8 floxed. (J:235787)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count