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Cre-mediated recombination of Clptm1ltm1c(EUCOMM)Wtsi removed exon 3, creating a frame shift mutation with a stop codon immediately downstream. No mRNA transcripts were detected in lipopolysaccharide (LPS) stimulated B cell cultures from homozygous mutant mice. Interestingly, the abundance of mRNA was greater in heterozygous B cell cultures than in wild-type cultures. (J:265892)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
