CRISPR/Cas9 technology was used to inject 4 gRNAs, two gRNAs targeting exon 1 and the other two to exon 2. Sequence between the gRNA targeting sites was deleted. Western blot analysis confirmed absence of protein. (J:271250)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count