A 3 kb genomic fragment of the mouse Hes5 gene, including 1.6 kb of the 5' flanking region (amplified from BAC clone RP23-333L21), was placed upstream of the Enhanced Green Fluorescent Protein (EGFP) gene. The transgene construct was injected into the male pronucleus of fertilized DBF1 oocytes. Three stably expressing lines were established: 21, 27 and 48. The pound # sign is used in the allele symbol where the line is not specified. (J:119796)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count