The first loxP was inserted into the 5' region upstream of transcription initiation site, and second loxP together with neomycin cassette was inserted into intron 1. The Neo-cassette was removed using FLPeR mice, leaving exons 1 floxed. (J:271100)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count