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Cre-mediated recombination removed LSL-STOP sequence from Hip1tm5.1(HIP1)Tsr resulting in expression human HIP1 and a GFP reporter. GFP expression was detected in peripheral blood white blood cells of homozygous mutant mice. Western blot analysis confirmed the expression of human, rather than mouse, HIP1 protein in lung tissue from homozygous mutant mice. (J:267987)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
