A loxP site was inserted upstream of exon 2 and a FRT-flanked neomycin cassette followed by a second loxP site were inserted between exons 5 and 6. Flp-mediated recombination removed the selection cassette, leaving exons 2-5 floxed. (J:239857)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count