BAC RP22-455H18, from a 129S6/SvEvTac genomic library, was micro-injected into C57BL/6J one-cell embryos. The BAC contains the complete Nnt gene (plus flanking sequence, possibly including (parts of) flanking genes). Two independent mouse lines were established: B6-TG1 and B6-TG2. In both lines, the transgene complements the NntC57BL/6J null allele. (J:109356)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
--
Insertion
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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