Exon 18 was replaced by a loxP flanked exon 18 and FRT-flanked neomycin resistance gene via homologous recombination. Cre-mediated recombination deleted exon 18, leaving the neomycin gene. (J:247259)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count