Log In|Sign Up
EN
The transgene contains a PCR-generated 4.3kb fragment of the human HBB gene (912-5200) containing HS3 and HS4 of the human beta-globin locus control regions (LCR) inserted into a 12.4-kb fragment of the human HBB gene (32837-45203) including the mutant human HBG2 gene with a T at position -158 relative to the cap site, the HBG1 gene and the 3' enhancer. Founder line G203 was established and found to have multiple copies of the transgene. (J:66961)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
