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The targeting construct is designed to insert a GFP reporter-GSGGS-OVA(229-359) fusion protein followed by an ACN cassette into exon 2 (the natural translation start site) of the gene. The ACN cassette includes a neomycin cassette, Cre recombinase and testes specific promoter (tACE) flanked by loxP sites. The tACE promoter allows expression of cre during spermatogenesis resulting in removal of the ACN cassette. (J:269925)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
