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EN
The transgene construct comprises the following elements: the mouse keratin 18 promoter/enhancer, the coding portion of the human TAR DNA binding protein cDNA, sequence coding for myc tags, and synthetic poly(A) sequences. The transgene was micro-injected into C57BL/6 eggs. In this allele the keratine promoter drives the expression of the C-terminally myc-tagged TARDBP gene. (J:269757)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
