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EN
The transgene construct that was micro-injected into fertilized eggs conatins the following elements: the CAG promoter-enhancer, a loxP site flanked neomycin resistance gene cassette (which includes p(A) sequences), and the human interleukin 1 alpha gene. This creates a conditional-ready allele where the human gene is only expressed after the deletion of the neo cassette through cre-mediated recombination. (J:269353)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
