Using IKMC targeting vector PRPGS00028_A_A10, a lacZ gene expression cassette and a loxP site flanked neomycin resistance gene cassette were inserted into intron 4. A third loxP site was inserted into intron 5. The neo cassette and exon 5 were deleted through subsequent cre-mediated recombination, leaving a reporter knockout allele. (J:269106)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top