The transgene consists of a modified BAC RP11-578M14 (184 kb) in which a neomycin resistance cassette replaced the GNB3 gene. The modified BAC contains 13 human genes (MLF2, CD4, PTMS, LAG3, COPS7A, GPR162, P3H3 (LEPREL2), CDCA3, USP5, TPI1, SPSB2, RPL13P5, and DSTNP2) from 12p13.31. One line was generated. (J:201055)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count