The targeting vector is designed to insert a loxP site upstream of exon 8, and a second loxP site downstream of the 3' untranslated region (UTR). The construct, also contains an FRT-flanked neomycin selection cassette.Flp-mediated recombination removed the FRT-flanked neo cassette. (J:268958)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count