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CRISPR/Cas9 editing was used to introduce three nucleotide changes, including two nucleotide changes in codon 379 (GGT > CGC) resulting in substitution of arginine for glycine at position 379 (G379R), and a silent change in codon 377 to disrupt an adjacent PAM site (ACC > ACA). (J:296318)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
