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A 26-bp deletion of chromosome 11 (60,778,048-60,778,073) in exon 1 of Smcr8 was created using the CRISPR/Cas9 system and sgRNA 5'-GGGATCTTCGTCTTCTGACG-3'. This deletion result in a predicted frameshifted protein product beginning after amino acid 7 of the protein and terminating after the inclusion of six aberrant amino acids. (J:268243)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
