BAC BMQ-448E21 carrying the genomic Cdkn1a mouse sequence was modified to replace the stop codon in exon 3 with a tdTomato reporter followed by polyA sequence. A loxP-STOP-loxP (LSL) cassette was inserted into intron 2. The transgene inserted on the centromeric region of chromosome 6. (J:266858)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count