Vkorc1l1^em1(IMPC)J

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TCCATGACTGATTTGCGCAA and TTTACTATGAAGACACACTA, which resulted in a 325 bp deletion beginning at Chromosome 5 position 129,978,373 bp and ending after 129,978,697 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000410731 (exon 2) and 215 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 65 and early truncation 62 amino acids later. (J:188991)