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This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCAGTGTCCCAAATGAAGAA and CTAGCTTAGCATCTGATTAG, which resulted in a 403 bp deletion beginning at Chromosome 2 position 180,283,188 bp and ending after 180,283,590 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000369913 (exon 3) and 360 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 20 and early truncation 5 amino acids later. (J:188991)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
