Exon 5 was flanked by loxP sites. A neomycin-resistant gene flanked by two FRT sites was inserted next to the 5'-loxP site. Flp-mediated recombination removed the neo cassette leaving exon 5 floxed. (J:252857)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count