This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCAAAGTCTCCAAAGCACCT and GCTCTGAGTAAAGGTACAGA, which resulted in a 510 bp deletion beginning at Chromosome X position 74,151,956 bp and ending after 74,152,465 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000495133 (exon 4) and 374 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 246 and early truncation 1 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count