The mouse BAC (CITB-31B1) did not contain the complete Usp9y gene. The BAC was modified to add missing exons 23-47 by recombineering spliced cDNA sequence into the sequences. This modified BAC was used to make transgenic mice. Two lines were generated with 20 and 22 copies, respectively, of the transgene. (J:171865)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count