This TALEN-mediated mutation of nucleotide 3443-3487 was generated in the rd8 mutant allele and is a 45 bp deletion in exon 9 that restores the reading frame that was disrupted by the single base pair deletion of the rd8 mutation and causes a 15 amino acid in-frame deletion followed by a single amino acid substitution and causes a less severe phenotype than the rd8 mutation. (J:265859)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Crb1rd8 Jak3m1J/BocJ
Endonuclease-mediated
Intragenic deletion
Not Specified
1
12
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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