This TALEN-mediated mutation of nucleotide 3443-3487 was generated in the rd8 mutant allele and is a 45 bp deletion in exon 9 that restores the reading frame that was disrupted by the single base pair deletion of the rd8 mutation and causes a 15 amino acid in-frame deletion followed by a single amino acid substitution and causes a less severe phenotype than the rd8 mutation. (J:265859)
Basic Information
B6.Cg-Crb1rd8 Jak3m1J/BocJ
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count