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The rat promoter drives the expression of the mouse gene in lung epithelium. The gene is constructed by fusing 170 bp 5' cDNA sequence to the remainder of the gene's genomic sequence (including ~1.2 kb 3' flanking sequence). Of the three founder lines - NJ.1659, NJ.1723, NJ.1726 - the latter was found to have the highest copy number and expression and severest pathology and was chosen for further study. (J:41589)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
