This differentially methylated region between Dlk1 and Gtl2 was targeted with four transcription activator-like effector-based nuclease (TALEN) mRNAs flanking the 216 bp CpG-rich tandem repeat array in the center. Line T334 showed a 336 bp deletion that includes the entire repeat sequence. (J:266963)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F2
Endonuclease-mediated
Intergenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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