Exon 2 was flanked by loxP sites. A PGK-neomycin selection cassette flanked by FRT sites was removed via Flp-mediated recombination. (J:266893)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count