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This allele from project TCPR1074 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of ATGGTTGGAATCGTGCTGTC and CGTTCCCTGAGGTAGTCCTA targeting the 5' side and CAAGTGAGGAGAACTGCGTG targeting the 3' side of a critical exon. This resulted in a 5-bp deletion of Chr18 from 75082183 to 75082187 and a 309-bp deletion of Chr18 from 75082260 to 75082568 (GRCm38). (J:265051)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
