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This transgene contains the HOD antigen composed of in frame fusion of the complete open reading frame of hen egg lysozyme (LYZ) minus the stop codon, chicken ovalbumin (OVAL) open reading fram encoding amino acids 251 to 349 minus the stop codon, and the complete open reading frame of human ACKR1 (also known as Duffy) under the control of the human red blood cell specific beta-globin control region (mu'LCR) and the beta-globin gene intron 2 and 3' enhancer. A founder with germline transmission was established and assign as line 1. (J:152426)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
