A bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-27F7) containing the entire mouse parathyroid hormone-like peptide (Pthlh) gene. This BAC was modified to replace the native start codon of the Pthlh gene with a cre/ERT2 fusion gene (Cre recombinase fused to a human estrogen receptor ligand-binding domain), followed by an SV40 polyadenylation sequence. (J:266751)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F1
--
Insertion
--
--
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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