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The alpha-tropoyosin containing a substitution of an aspartic acid for asparagine at residue 230 (D230N) is under the control of the cardiac specific rat alpha-myosin heavy chain promoter. This is the high-expressing line that expresses about 69% of the total Tpm1 as the mutant transgenic form. (J:243724)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
