This transgene consists of the rat Kcnj8 cDNA under the control of the CX1 promoter which contains the chicken beta-actin promoter followed by the enhanced green fluorescent protein coding region (including a stop codon) flanked by loxP sites. EGFP is ubiquitously expressed unless Cre-recombinase is expressed which excises the EGFP and results in expression of Kcnj8. Lines 1 and 2 are the high expressing lines, with line 1 entered as the representative line. (J:202037)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x CBA
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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