This transgene consists of the rat Kcnj8 cDNA under the control of the CX1 promoter which contains the chicken beta-actin promoter followed by the enhanced green fluorescent protein coding region (including a stop codon) flanked by loxP sites. EGFP is ubiquitously expressed unless Cre-recombinase is expressed which excises the EGFP and results in expression of Kcnj8. Lines 1 and 2 are the high expressing lines, with line 1 entered as the representative line. (J:202037)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count