The murine Hmga1 coding sequence is under the control of the murine H2-K promoter and immunoglobulin mu intronic enhancer which drive expression in B and T cells. Western blot analysis confirmed increased protein levels of Hmga1 in splenocytes. Seven lines were generated and the pound symbol (#) is used because line numbers are not specified although the line with 20 copies of the transgene is used most often. (J:90252)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count