LoxP sites were introduced to introns 4 and 6. An FRT-flanked neomycin cassette adjacent to the 5' loxP site was removed by Flp recombinase-mediated recombination, leaving exons 5 and 6 flanked by loxP sites. (J:328905)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count