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Sequence for codons 1-287 and 422- 805 was ligated and placed downstream of tetracycline responsive elements (TRE) and a minimal CMV promoter. The gene is followed by SV40 poly(A) signal sequences. The gene is only expressed, in a tetracycline/doxycycline controllable manner, when mice carrying this allele also carry a tTA or rtTA allele. (J:265654)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
