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The line was generated by inserting a cDNA encoding IRES-Dre recombinase fused with a mutant form of estrogen receptor hormon-binding domaine C (ERT2) into in-frame with the translational termination codon of the last coding exon of Alb by homologous recombination using the CRISPR/Cas9 technology. This knock-in strategy leads to simultaneous expression of DreER and endogenous albumin. (J:263751)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
